Flonase Side Effects


Flonase (fluticasone) is a synthetic steroid of the glucocorticoid family of drugs and is prescribed for the control of symptoms of allergic and non-allergic rhinitis. Flonase is available as a generic drug, and dosing is usually administered as two sprays in each nostril once daily, or one spray in each nostril twice daily.

The most common side effects of Flonase (fluticasone) include:

  • headache,
  • back pain,
  • sore throat,
  • sneezing,
  • cough,
  • nausea,
  • vomiting,
  • menstrual problems,
  • loss of interest in sex,
  • nosebleeds,
  • sinus pain, and
  • sores or white patches inside mouth or around your nose.

Flonase has also been associated with hypersensitivity reactions (for example, skin rash, itching, facial swelling, and anaphylaxis).

The recommended starting dosage of Flonase in adults is 2 sprays (50 mcg of fluticasone propionate each) in each nostril once daily (total daily dose, 200 mcg). Drug interactions and warnings include Norvir (ritonavir) and Nizoral (ketoconazole). Taking either one of these drugs with Flonase may increase the blood concentrations of Flonase and potentially increase its side effects. Flonase should only be used during pregnancy when it is absolutely necessary. There have not been adequate studies of Flonase and concentrations in breast milk; therefore, Flonase should be avoided while breastfeeding unless it is absolutely necessary.

Our Flonase Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.


FLONASE® Allergy Relief is meant to work in your nose. Never use in your eyes or mouth.

If you or your child have an allergic reaction to this product, with sudden swelling of the face or tongue, a rash, or wheezing or feeling faint, stop using FLONASE® Allergy Relief and see a doctor right away.

If you or your child experiences a nose injury with severe or frequent nosebleeds, apply pressure to your nose. Stop using FLONASE® Allergy Relief and see a doctor right away.

If you or your child experiences a constant whistling sound that does not go away, this could be a sign of damage to your nose. Stop using FLONASE® Allergy Relief and see a doctor right away.

If you or your child experiences cloudy or reduced vision, it could be the result of eye conditions such as cataracts or glaucoma. Be sure to schedule a yearly eye exam to check for these conditions.

If administering to your child, talk to their pediatrician if you are concerned they may experience certain growth effects, such as a slower growth rate as a result of using FLONASE® Allergy Relief. Also, speak to your doctor if your child is between the ages of 4 and 11 needs to use FLONASE® Allergy Relief for longer than 2 months a year.

Talk to your doctor or pharmacist if you or your child experiences other side effects such as headaches or sneezing, a bad taste or smell, minor nosebleeds, or a dry or irritated nose or throat.

Finally, please read the Drug Facts on the back of the FLONASE® Allergy Relief or package to be aware of any additional information that may be helpful to you. If you have any concerns about side effects, talk to your doctor.

Use as directed. Please see specific products for full labeling information.

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